| Retrocopy Name | CHMP1 |
|
| Species | Homo sapiens | |
| Coordinates (hg38) | chr1:241633907-241635118 UCSC | |
| Coordinates (T2T) | chr1:241045381-241046592 UCSC | |
| Coordinates (hg19) | chr1:241797209-241798420 UCSC | |
| Strand | - | |
| Parental Sequence | NM_001362519.1 | |
| Parental seq. overlap | 999 bp | |
| Parental seq. overlap (%) | 17.9% | |
| Genomic Region |
Intergenic |
|
| Retrocopy Summary | CHMP1, located on chr1:241633907-241635118, is a retrocopy of the parental gene CHM. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes. |
| Gene Name | CHM |
| Full Name | CHM Rab escort protein |
| Also known as | DXS540|GGTA|HSD-32|REP-1|TCD |
| Coordinate | chrX:85861180-86047558 |
| Strand | - |
| Gene summary | This gene encodes component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme, this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction. Rab GTPases need to be geranylgeranyled on either one or two cysteine residues in their C-terminus to localize to the correct intracellular membrane. Mutations in this gene are a cause of choroideremia; also known as tapetochoroidal dystrophy (TCD). This X-linked disease is characterized by progressive dystrophy of the choroid, retinal pigment epithelium and retina. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016] |
| >CHMP1 |
| ATTACTTACTCTCAAATAGTTAAAGAAGGCAGGAGGTTTAATATTGATTTGGTGTCAAAACTGCTGTATTCTCAAGGATTGCTAATTGATCTTTTAATCAAATCAGATGTTAGTCGTTATGTAGAATTTAAAAATGTCACTAGGATTCTTGCATTTCGGGAAGGAAAGGTAGAACAAGTTCCTTGTTCCAGAGCAGATGTCTTTAATAGCAAGGAACTCACCATGGTTGAAAAGAGGATGCTAATGAAATTTCTCACATTTTGTTTAGAGTATGAACAACATCCTGATGAATACCAAGCTTTCAGGCAGTGTTCATTTTCAGAATACTTAAAAACTAAAAAACTAACTCCCAACCTTCAACATTTTGTACTGCACTCAATTGCAATGACATCAGAATCATCTTGCACTACAATAGATGGTCTTAACGCAACTAAAAACTTCCTTCAGTGTCTCGGACGGTTTGGCAACACCCCCTTTTTATTTCCCTTGTATGGCCAAGGAGAAATTCCCCAGGGTTTCTGTAGGATGTGTGCAGTTTTTGGTGGAATCTATTGTCTTCGTCATAAAGTACAATGCTTTGTAGTCGACAAAGAATCTGGACGATGTAAAGCAATTATAGATCACTTTGGTCAAAGAATAAATGCTAAATATTTTATTGTGGAAGACAGTTACCTTTCTGAGGAAACATGCTCAAATGTGCAGTATAAGCAGATCTCTAGGGCAGTACTCATTACAGATCAGTCTATACTAAAGACAGATTTAGATCAGCAGACTTCCATTCTGATAGTTCCTCCAGCAGAGCCAGGAGCTTGTGCTGTACGGGTCACAGAATTATGTTCTTCAACCATGACATGCATGAAGGACACCTATCTGGTACATTTGACATGTTCATCTTCTAAAACAGCAAGAGAAGACTTAGAATCAGTGGTGAAGAAATTATTCACTCCGTATACTGAAACAGAAATAAACGAGGAAGAACTTACAAAGCCAAGACTCTTGTGGGCTCTTTATTTTAATATGAGAGATTCCTCGGGAATCAGCAGAAGCTCGTATAATGGCTTGCCTTCCAATGTTTATGTCTGCTCTGGGCCTGACTGTGGCCTGGGAAATGAGCATGCTGTCAAGCAAGCTGAAACACTTTTCCAGGAGATCTTTCCAACTGAAGAATTCTGCCCTCCACCTCCAAATCCAGAAGACATTATCTTTGATGGT |
| >NM_001362519.1 |
| GGCAGTTACAGGGAGGGGCTGGGACCCGCAGTGCTTATCGCCATTTGAGTAGGGGTTGATCTGGTCGATGCTGATTGCTGAGGTTGGTTGCTGCGGTGATTCCTGTTAATTTCCTTAGAGGGAAGTGGATGTGCAGTGTCATGAAATGGAGGGTCGGGATTTTATCAACGGAGACGACTTTGGCAAGACATTATGATTCCTTCCTTATTGATTTCAAGGTTTGCCTGAATCCATCATTGCAGCTGCATGTTCAAGAAGTGGCCGGAGAGTTCTGCATGTTGATTCAAGAAGCTACTATGGAGGAAACTGGGCCAGTTTTAGCTTTTCAGGACTATTGTCCTGGCTAAAGGAATACCAGGAAAACAGTGACATTGTAAGTGACAGTCCAGTGTGGCAAGACCAGATCCTTGAAAATGAAGAAGCCATTGCTCTTAGCAGGAAGGACAAAACTATTCAACATGTGGAAGTATTTTGTTATGCCAGGATTTGCATGAAGATGTCGAAGAAGCTGGTGCACTGCAGAAAAATCATGCTCTTGTGACATCTGCAAACTCCACAGAAGCTGCAGATTCTGCCTTCCTGCCTACGGAGGATGAGTCATTAAGCACTATGAGCTGTGAAATGCTCACAGAACAAACTCCAAGCAGCGATCCAGAGAATGCGCTAGAAGTAAATGGTGCTGAAGTGACAGGGGAAAAAGAAAACCATTGTGATGATAAAACTTGTGTGCCATCAACTTCAGCAGAAGACATGAGTGAAAATGTGCCTATAGCAGAAGATACCACAGAGCAACCAAAGAAAAACAGAATTACTTACTCACAAATTATTAAAGAAGGCAGGAGATTTAATATTGATTTAGTATCAAAGCTGCTGTATTCTCGAGGATTACTAATTGATCTTCTAATCAAATCTAATGTTAGTCGATATGCAGAGTTTAAAAATATTACCAGGATTCTTGCATTTCGAGAAGGACGAGTGGAACAGGTTCCGTGTTCCAGAGCAGATGTCTTTAATAGCAAACAACTTACTATGGTAGAAAAGCGAATGCTAATGAAATTTCTTACATTTTGTATGGAATATGAGAAATATCCTGATGAATATAAAGGATATGAAGAGATCACATTTTATGAATATTTAAAGACTCAAAAATTAACCCCCAACCTCCAATATATTGTCATGCATTCAATTGCAATGACATCAGAGACAGCCAGCAGCACCATAGATGGTCTCAAAGCTACCAAAAACTTTCTTCACTGTCTTGGGCGGTATGGCAACACTCCATTTTTGTTTCCTTTATATGGCCAAGGAGAACTCCCCCAGTGTTTCTGCAGGATGTGTGCTGTGTTTGGTGGAATTTATTGTCTTCGCCATTCAGTACAGTGCCTTGTAGTGGACAAAGAATCCAGAAAATGTAAAGCAATTATAGATCAGTTTGGTCAGAGAATAATCTCTGAGCATTTCCTCGTGGAGGACAGTTACTTTCCTGAGAACATGTGCTCACGTGTGCAATACAGGCAGATCTCCAGGGCAGTGCTGATTACAGATAGATCTGTCCTAAAAACAGATTCAGATCAACAGATTTCCATTTTGACAGTGCCAGCAGAGGAACCAGGAACTTTTGCTGTTCGGGTCATTGAGTTATGTTCTTCAACGATGACATGCATGAAAGGCACCTATTTGGTTCATTTGACTTGCACATCTTCTAAAACAGCAAGAGAAGATTTAGAATCAGTTGTGCAGAAATTGTTTGTTCCATATACTGAAATGGAGATAGAAAATGAACAAGTAGAAAAGCCAAGAATTCTGTGGGCTCTTTACTTCAATATGAGAGATTCGTCAGACATCAGCAGGAGCTGTTATAATGATTTACCATCCAACGTTTATGTCTGCTCTGGCCCAGATTGTGGTTTAGGAAATGATAATGCAGTCAAACAGGCTGAAACACTTTTCCAGGAAATCTGCCCCAATGAAGATTTCTGTCCCCCTCCACCAAATCCTGAAGACATTATCCTTGATGGAGACAGTTTACAGCCAGAGGCTTCAGAATCCAGTGCCATACCAGAGGCTAACTCGGAGACTTTCAAGGAAAGCACAAACCTTGGAAACCTAGAGGAGTCCTCTGAATAATGGATATACACCAAACTGGATACCCAACTTTGGAAATTCTGACTGGTCTCAGAGTCTACTTGATAGAAGGACTGTTTGAGAAATGTTAGAAAGCAGCAGCAATTATAAGGCAAAATAGGTAATAGAAATCCAAAAGGGGATTTTCCTTATAGAGGACATTCCAAGAACACACAACACTTATAAAGCACATTGACTTGCTCATTTTAAATACCAAACTTGTGTGACTAGCAGATGAAAATTATAAATCAATTGATTCTCAGGAATGTAACTGTGGATATGAAAGTGATCCTATGCATTGTTAATAATTCCATGGTCTTAGGACAATTTTGCTTACCACTTTGGATCTTTGTTTGAAAGCCACATTTTCAGAACCAGCTCATGTATTTTCTTTGGTTATTTGAATTTTATTTTCTTTATGGACAAGAGCATCATAACATAATGATAAAAACATATAGAAAAACTAAAGTATCATGATCTAGATAGAAGCCTGTATTTGGAATACAGGTTTGTTTTGCTTTCTATGTTGAGAAGCATTGAAAATGCTAATATAAAGGTGTTTAGACATTTTTACGAATAAGTCAGTAGTGTTTTTTAGTATCAGTAGTGATATTTGTTTGTAAATTATTTACATATTGGGAAAGGTCAATAATGAAGAAATGAAAGAATGGAAGGAAAGGTGTGGATAGGCTCATTGGTATTTGAATATTCTGTCTgtcaagtaactagagtattaggctaattgtctacagacctaatttaatcctggctgtcctactgatgatatttggtaaattgtttaacttctgagcctacgtttctccatatataaagtggaaatagtattactatgcctactatatgagaatggttatgaagacaatgcaatgccatgtttagaatcggtttgCCAGAAGAAAATTGTTTTAGAATTTTCCCATTGACTTGATGAATCTCAAAAGTCTCACGCAGGAAATAATTGCTTGCTGTCAGTCAACTTCCAAACAAAATAGATCACAGTGTTTTTATTGCATTAAGCTTTTTAAATGAAAATTTCTTTTTTAAAGTAGTATTTTATAGTCTTACAGACCAGTAAAAATAGTAACAAGTAGAATTGTGGTTTTGAAATATTACTAAGGAAAACACTCTATAAATTGTTTTATTCCTTTTCTGGTAGGTAAACCTGCAACCACCAAGGACTCCAAATTGTGTATGACAGTTGGTAAGCCCTAATATACACTACATAAAAACGTTAGGGCTgcctgtaatcccagcactttgggaagctgaggtgggtagatcacttgaggtcaggagttcgagaccagcctggccaacatggcgaaaccctgtctctactaaaaatacaaaattttagctgggtgttatggtgggcacctgtaatcccagctactttgaagatgaggtagcagactcacttgaaccagggaggcggaggttgcagtgagccaagattttgccactgcactccagcctgggtgacagagcaagactctgtctcacaaaaaaaaaaaaaGGGGGCTGTACATAGGCAGCAAACTAAGCTGCAGTGATGTTGCCTATATTTAAATTTTCTCAAATGGCCAAGCTCTGATGGTCTACTTTATTTGAGCAATAGTTGAGACTTATAATTGCCTATAAATAAACAAACAAATGAACTATTTGTTTTTTTTTCTCACAACATCTGGCCTATATTGTCTGTCAGGAAGCCATGGCTCCAATGTAAAGTACATAGTTCTTACATACTTCAACTGCAGCTGGTCCCTGACCTCACCAGGTTTCAGAGATGTTCTTAAAGGAAGCCAGCTGTGGCAGGTCACAGATTCATGGGAAATGGAAAGAACCAAGGAATATAGCTCTTGCCTCACCTTTCTACCCACTGCAGATATAGTTCAAGCCAGAGTAATGGAAGAACTTAACTTACTAGCCTCTCAGGCTGCTCCTATCCCTACCTCCCAGTGTACAGCCCCTCCCCATCTCTTTAGTCCCCTTTCCCTCACTTCCCCTTTTATAATGTCACACAAATCAGGGACAGTAGGATCACATTATAACCTACTTTGTCATAGGGATTCGATTTTTCTTATATCAAATCATGTTTCCTGAAACCCAGCTGGGGCATATGCACTCAATGTCTAATACATACTTATTAATGTACCGGATATTGGCCTTGCCCCTGGATATCAGCAATATATTATAAAAGGTTCCAGTAGATGAGACGattgagtctgaatacaattgcagtaaattgtgccaataaagatattgtactgttacggtcttagagttaaagccgcttgaatgcagcatgcacattcatgtaaaCAGACAATCAGGGTAGGCCTAGAATAACCACAAAAATTCTATTGGCCTTACTGCAGCCACCTATATGTAGAACAATGGAGGAGATAGTTTGTGGTCCATTATTGTACCCTGTTTCATCCATTAGCATCAGAATCTCTCTTTCAGGTCATTTATTAAATATGATTGAAATGTTTAAAAGTTCCTGAACATGATTCATGATGATTAAAATATCATACAACTGATAAAAGACTTTAAGAACTTTATATATTTCCTGTTGCCTCAAAATGTAACAGAAATTATTCTTAGAGCTTTGATTTTAGCTATCCTAATTACTGCAAATAAATATTTGTTCTTATAGTTTTAAATCAAAAAGAAAAGTCTTGTTATAAAACCTTAAGCTTGAAATCATATTAATAAAATATATTGTACATAGTGGAAAATTTTCAGTAGCTAATTTAAAATTTCAGAAAATGCTATTAAAGAATTTTGATTCAAGTATTTAAACTGTTTAGTTATGCATGCTTCTTATTAACCGAAAATGATAATACCATTTAGTTTAGTGATCAGTATGAGAAGCAATACCTAATCCTATGTTGCTATTGTATTTTTTCCTAGTTGGTGTGCCTGCTCAGAAAAACATATACTGTATGTGTATACATACCTGTGTATATATAAAAGGTCAATTTATATATTTTTCTATAGGAAAATGGAGTAACAAGTTCCCTATCTCCCATATTTATTTGTCCATAGTAAAATGGCCACATTGATGATAATTTCTAGAACTAGTTTCTGAGATTGTCAGCCCTTTGTCTAAAATAATGGCAGTATTAATGATTGACTTCTGTCACTGCCATAGTTACCTGGATTGTCAGCCTTGGTAGCCTTTGTCTAAAGTCCTAAAGAGTTCCAAAAAAAATGTGTTGAAATTTAATTGCTAAATAGTGGTTGGTGATTCTTTACAGTAGGAATTGTAATAATTTTCTTGCAAATAAGTTATTTACTGCTATTGATATTGAATAATTTGTCTTTTATTCAGATATATTTCAAAAAGCATGAATATATGATTATTCATAAATTGTATACTTTACCAGTAAGTTTTCAGAGGAAATAAAGACTTTTAAATCCTTTTCA 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